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Indeed, the evidence also suggests that IGF1 plays a critical role in DM by lowering blood glucose levels and insulin secretion (217)
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The iron overload increased the lipid peroxidation approximately by 2, 3 and 4 folds in the mice kidneys receiving 5000, 10,000 and 20,000 ppm of ferric chloride for 30 days ( Table 5 )