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This suggests that the observed activation in many brain regions is indirect likely triggered by the drug binding in more accessible areas, such as the circumventricular organs, which then transmit signals to other parts of the brain
Diabetes & Endocrinology
AAPS PharmSciTech (2011) 12(3):93848
Daru 21 (1), 54
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1 Figure 1 shows the numerous physiological effects of GLP-1 agonists, affecting a wide range of systems including the brain, muscle, pancreas, liver and heart
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