This reduced binding may affect its bioavailability and interactions with target tissues in experimental models
Then the authors isolated single hippocampal stem and progenitor cells by FACS followed by single-cell RNA-seq
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It blocks the synthesis of DNA, mRNA, and protein synthesis by interacting with purine bases on gDNA or mitochondrial DNA, inhibiting DNA replication and promoting cell apoptosis ( A previous study has found that QUE enhanced the growth inhibition of CIS in HepG2 HCC cells by up-regulating p16 expression ( As an effective chemotherapeutic agent, CIS is used to treat various human cancers
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Quite simply, a glutathione deficiency is a marker of mitochondrial dysfunction and oxidative stress