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On the contrary, MC4R agonist, setmelanotide, was approved for the rare MC4R-deficiency, BardetBiedl syndrome (BBS), with severe obesity in childhood [10, 23]
Later on, the FDA withdrew its approval in 2008 because of commercial reasons unrelated to its safety and efficacy
Waqar MA (2025) A comprehensive review on recent advancements in drug delivery via selenium nanoparticles
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