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50 Excess ROS lead to oxidative stress, which can damage DNA, proteins, and cell membranes
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2018;28:547e3
Most preclinical studies use animals with experimentally controlled metabolic states that do not reflect the heterogeneity of real addiction populations
Moreover, in a porcine model, exenatide is ascertained to attenuate cardiomyocyte apoptosis and oxidative stress levels, which plays a role in curtailing the myocardial infarction area and precluding the impairment of cardiac systolic and diastolic functions [98]
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