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The subsequent increase in ATP/ADP ratio leads to a closure of ATP-sensitive K + channels, intracellular accumulation of K + ions and subsequent membrane depolarization, causing an influx of Ca 2+ via voltage dependent Ca 2+ channels (VDCC)
(b) Three-chamber test assessment of social novelty, with results shown for normal C57BL/6J mice following vehicle control (n = 7) or MT-II treatment (n = 6), and MIA mice following vehicle control (n = 7) or MT-II treatment (n = 8)
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While cytosolic and blood GSH and Cys biochemical species all experience depletion, the model predicts that a single exposure to doxorubicin only results in a minimal perturbation of the antioxidant defence system
[9] Among Native American tribes, the Gila monster has a varied reputation
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