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Did a placebo group deteriorate unexpectedly
Excess weight and insulin resistance can disrupt ovulation, alter hormone levels, and contribute to conditions such as polycystic ovary syndrome (PCOS)
Applications require income documentation and a Kaiser prescriber's signature confirming medical necessity [13]
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Large-scale randomised controlled trials such as the STEP programme (semaglutide) and SCALE trials (liraglutide) reported pancreatitis as an uncommon adverse event (occurring in 0.1-1% of patients), with no clear signal for increased risk compared to placebo
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