Altogether, these insights position GLP-1RAs as promising modulators of atherosclerotic disease and highlight the need for targeted mechanistic and clinical research to fully define their vascular impact
Newsome P, Francque S, Harrison S, et al
If nausea arises when GLP-1 RA plasma concentrations are at their peak, then continuous exposure to GLP-1 RAs may lead to tachyphylaxisa reduced response to the drug over timeresulting in fewer gastrointestinal symptoms after long-term use [20]
McIntyre RS, Mansur RB, Rosenblat JD, Kwan ATH
Positive effects on motivation and mental health and the value of avoiding bariatric surgery were also discussed
Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism