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All data were available in TCGA database and GEO databases

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Innate immunity involves immediate, nonspecific responses to foreign invaders, while adaptive immunity requires more time to develop its complex, specific responses (1)

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Protects the body from free radicals that cause oxidative stress

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Search strategy and selection criteria A systematic literature search was conducted across four major databases: PubMed, Web of Science, Scopus, and Embase, covering publications from January 1997 to April 2025

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S.CostantiniI.BaracchiD

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