In fairness, the gradual build-up isn't necessarily a bad thing
It has been reported that the administration of VD up-regulates CBP expression in the brain through VDR-mediated promoter activation, resulting in improvements in memory and cognition [99]
Decreasing the dosage often diminishes or eliminates drug-related patient body odor or gastrointestinal symptoms when present
Once an oral small-molecule GLP-1 is approved, there may be an expectation that it will take over from the current peptides
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doi: 10.1016/j.apsb.2024.10.008 171 LiJLJiangJYGuSSZhangLSunYWangXHet al