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Diarrhoea may occur in some individuals, particularly with higher-dose supplements
Monitoring-guided supplementation is the usual approach, typically beginning with oral supplementation if blood tests indicate suboptimal levels, and escalating to IM injection if oral treatment is insufficient or poorly tolerated
They require proper technique, clean supplies, and comfort with needles
Most acute side effects are dose-dependent and rate-dependent
Some letters state that the reason B12 injections are being stopped is many patients are being over treated with this vitamin
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