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Expected contraindications will likely mirror existing semaglutide contraindications: personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia type 2 (MEN 2), active pregnancy, or severe pancreatitis history
Suitable For: Adults (18+)
Clinical studies document sustained improvements over extended use
Clinical Markers for Treatment Effectiveness We watch for signs of success by checking clinical markers
Any of these make an auto-immune cause of B12 deficiency (PA, also called autoimmune gastritis 3 ) more likely
Restart timing remains unsettled because trials have not measured re-titration after a prolonged stop
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