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93 Deficiency of GAPDH seems a rare occurrence without functional consequences

At high doses, unabsorbed carnitine can pull water into the intestines, leading to gastrointestinal distress, including nausea, abdominal cramps, or diarrhea

Panchal, S

Smith JP, Stock H, Bingaman S, et al

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First, proteins containing N-methylated lysine residues are degraded by lysosomes or proteasomes to release 6-N-trimethyllysine (TML), in which lysine provides the carbon backbone and nitrogen atom of carnitine, whereas methionine provides the methyl group