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The consequences of PPAR activation by bempedoic acid is enhanced hepatocyte fatty acid -oxidation and a consequent reduction in lipid content in the hepatocytes
First, a bacterial reverse mutation test (Ames test) assessed AOD9604s mutagenic potential using four histidine-dependent auxotrophic mutants of Salmonella typhimurium (TA1535, TA1537, TA98, TA100) and one tryptophan-dependent auxotrophic mutant of Escherichia coli (WP2 uvrA), using both plate incorporation and pre-incubation methods at doses of 0, 1.6, 8, 40, 200, 1,000, and 2,000 g AOD9604/plate
Keep B12 in its original carton, away from light, and never freeze it, as freezing damages the vitamin
The purity figure printed on each batch's Certificate of Analysis is the actual value recorded in the laboratory for that batch, not a generic marketing claim
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