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Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
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Given the reported anti-inflammatory effect of TREM2 in the brain, the R47H substitution may lead to an increased predisposition to AD (Jonsson et al., 2013
Upon ligand binding, these stimuli initiate the assembly of a key multi-protein signaling complex composed of receptor-interacting protein kinase 3 (RIPK3) and receptor-interacting protein kinase 1 (RIPK1), called necrosome