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This small molecule compound was developed through sophisticated structure-guided design and binding calculations as part of a systematic effort to create membrane-permeable NNMT inhibitors with enhanced potency and selectivity

These support the liver, which is central to fat metabolism

Theyre signaling molecules that play a role in various physical processes

"Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs"

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Description 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that consumes NAD+ precursors and is reported to be elevated in aged adipose tissue, obese skeletal muscle, and certain tumor types