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Beyond nausea, the gastrointestinal side effect cluster includes diarrhea, vomiting, constipation, and decreased appetite, which is technically a desired effect but can become problematic at extreme levels
Semaglutide also reduces inflammatory markers like C-reactive protein, which may benefit lymphatic health
"Even with a reduced appetite, it's important to prioritize nutrient-dense foods and adequate protein
For a complete guide, see our retatrutide side effects guide
Originally approved to treat HIV-related lipodystrophy, tesamorelin is now widely used off-label for fat loss, especially in the midsection
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