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SLU-PP-332 distribution The distribution pattern of SLU-PP-332 is characterized by: Rapid and extensive distribution to target tissues High volume of distribution, indicating good penetration into various body compartments Potential for crossing the blood-brain barrier, expanding its therapeutic potential These distribution characteristics may contribute to the versatility of SLU-PP-332 in treating various conditions
In addition, nicotinamide, the primary NNMT substrate 95,96 , is broken down by Lactobacillus arabinosis into nicotinic acid and ammonia 56
Transit times depend on the carrier and destination
When it becomes overactive, it essentially tells your cells to store more fat and burn less energy, while also depleting your valuable NAD+ reserves
Interestingly, we observed that the cecal microbiome of previously-obese animals returned to the lean state through NNMTi treatment and LD switch was distinct from the cecal microbiome of continuously lean control animals
Neither point is a claim that it works in humans
