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Peer review Peer review information Nature Mental Health thanks Karolina Skibicka and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

This breakdown covers how each medication works, real-world weight loss numbers, side effects, who should avoid each option, and practical tips to help you and your doctor land on the right fit

Likely yes, but not immediately

Henry Meds is a telehealth platform that takes a more streamlined approach to weight loss

Melanotan 2 is a synthetic peptide designed to mimic the effects of alpha-MSH, a naturally occurring hormone involved in melanin production

No clear liver injury appeared in trials