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First, human caSMCs also showed a 2-fold increase in cAMP release in response to GLP-1(2836), which was abolished in the presence of the sAC inhibitor KH7, but not the tmAC inhibitor Ddox (Figure 2H)

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[Abstract]2026 Jun:249:138-151

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This technique enables precise incorporation of modified residues such as Aib and D-2Nal, thereby contributing to the peptides stability and biological selectivity