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The dosing schedule of retatrutide is as follows: Weeks 1-4: 1 mg or 2 mg once weekly (starting dose) Weeks 5-8: 4 mg once weekly Weeks 9-12: 8 mg once weekly Week 13+: 8 mg or 12 mg once weekly (Maintenance Dose) However, some trial arms tested higher doses (up to 8 mg or 12 mg as the final dose)
Early studies have shown promising weight-loss results, which is why retatrutide has attracted so much attention
Slow down and watch for dehydration signs What diarrhea on GLP-1 usually feels like Diarrhea on GLP-1 can happen, and it can show up in a few familiar waysespecially if your stomach already feels sensitive
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In phase 2 trials, retatrutide achieved approximately 1718% weight loss in individuals with obesity without T2DM, surpassing most available pharmacotherapies 1,19
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