Between 1990 and 2000, results from clinical trials like the Diabetes Control and Complications Trial (DCCT), UK Prospective Diabetes Study (UKPDS), suggested that controlling intensive blood-glucose levels could reduce the incidence of microvascular complications, such as diabetic retinopathy, diabetic nephropathy, diabetic neuropathy
63,64,65 Under homeostatic conditions, microglia contribute to the regulation of numerous physiological functions, including neurogenesis, 66,67 angiogenesis, 68 maintaining BBB integrity, 69 synaptic pruning and remodeling, 70,71 synaptic transmission, 72,73,74 myelin health, 75,76 as well as phagocytosis and removal of apoptotic neurons and cellular debris
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For example, a Michigan woman credits Ozempic for urgent gastrointestinal symptoms she experienced that caused her to be hospitalized
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Its a GLP-1 analogue with a high degree of homology to the human hormone, and it acts as an agonist at its receptor: it binds to and activates the receptor the same way the natural GLP-1 your own gut releases after eating would