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While some preclinical studies with FGF21 and FGF21 analogs have suggested effects on bone turnover, clinical data have not demonstrated a consistent effect
It is challenging to accurately determine the potential risks and benefits without proper clinical trials and research
But are they really necessary and, more importantly, do they work as advertised
The FDA does not approve compounded medications for safety, quality, or manufacturing
Geroscience 47 (3), 44134427
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Reported effects include nausea, flushing, and headache, and PT-141 is not appropriate for people with uncontrolled high blood pressure or certain heart conditions
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