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A 2025 Phase I trial (Lee & Burgess, 2025) demonstrated that IV BPC-157 doses up to 20 mg were tolerated in healthy volunteers with no serious adverse events

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BPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and [PMID: 32445447] Laboratory literature summary: BPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and Enhancing Cytoprotection

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For comparisons with those compounds, see our does tirzepatide burn fat analysis