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Combining a compound with established Phase 3 long-term safety with a compound that has zero combination-specific safety data does not produce a combined profile that can be defended as long-term safe
Intravenous glutathione administration offers the highest bioavailability but requires medical supervision and is typically reserved for specific therapeutic purposes
More recently, glutathione-based chemical peel has also gained popularity.[] GLUTATHIONE AS A MESOTHERAPY Though there is lack of literature regarding the efficacy and methodology of use of glutathione as mesotherapy solution, it is widely being practiced by the dermatologists for treatment of melasma either as monotherapy or along with ascorbic acid, pyruvic acid, vitamin E, etc.[] TRANSDERMAL DELIVERY To enhance the permeability and reduce the foul odor associated with the topical applications of glutathione, Lee et al
In addition, other supplements can also support the natural synthesis of glutathione
Mughal, E
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