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High-resolution cryo-electron microscopy (cryo-EM) has successfully elucidated the exact spatial orientation and the precise residue-by-residue thermodynamic interactions that permit this unimolecular polypharmacology
This will lead to many people losing access to the medication and back to square one: weight loss through lifestyle change alone
Pro-apoptotic signaling of JNK1 is mediated by the upstream MAP3K apoptosis signal-regulating kinase (ASK1) cascade (147)
JAMA Intern Med 2014;174:19301933.ArticlePubMed 4
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We explore how athlete expression, public scrutiny and the IOCs rulebook collided on one of the worlds biggest sporting stages.
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