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(2024) 11:e01544
Tirzepatide acts as a dual agonist at the glucagon-like peptide-1 receptor (GLP-1R) and the glucose-dependent insulinotropic polypeptide receptor (GIPR), both members of the class B secretin-like GPCR family
Like TRT, sermorelin is only available by prescription
I'm not driven by food and thinking about what's for dinner and the next meal
It does not mean the dose is useless or dangerous, but it does mean that expectations should be calibrated accordingly
This dual agonism enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release when blood glucose levels are elevated, and slows gastric emptying
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