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Researchers believe this dual-action mechanism may explain why many patients experience greater average weight loss with tirzepatide compared with semaglutide

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Given the recent results of the CREDENCE trial, many patients will also be treated with an SGLT2-inhibitor, allowing the trial to study the combined use of these agents on renal outcomes

46,47 Despite promising outcomes, direct evidence for the impact of GLP-1 RAs on aging remains limited, revealing significant knowledge gaps, particularly as these agents gain popularity for weight management

Acute gastritis will generally resolve with at-home care