mb glp-1 RAs Reduce Inflammation and MACE Beyond Weight Loss | Farouc Jaffer posted on the topic The weight-loss-independent hepatoprotective benefits of

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doi: 10.1371/journal.pone.0048562 131

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These multifaceted roles of central GLP-1R activation may provide a plausible biological framework for understanding the spectrum of reported NAEs associated with GLP-1 RAs

Rats'appetites increase and their weight increases when the proglucagon gene, which encodes GLP- 1, is less expressed in the nucleus tractus solitarius [110, 111]