Having a closer look at the heat map illustrating the gene expression profile of PBMC, most of the genes showed massive changes in expression due to LPS injection, but were not affected by L-carnitine supplementation
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doi: 10.1023/B:JOEC.0000006473.26175.19 7 BallO
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Option (Evidence Strength: Grades B, B, C, and B) Amitriptyline (Evidence Strength: Grade B ) One randomized controlled trial reported efficacy of oral amitriptyline (25 mg daily titrated over several weeks to 100 mg daily if tolerated) to be superior to placebo (63% of treatment group clinically significantly improved compared to 4% of placebo group) at four months
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