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Wegovy 2.4 mg is available through specialist Tier 3 services with 6 to 24 months waiting times
Curated affinity data instead describe a full agonist at four of the five human melanocortin receptors: reported pIC 10.0 at MC1R, pKi 8.9 at MC3R, pKi 8.5 to 8.8 at MC4R, and pIC 9.0 at MC5R, with no activity at MC2R, the adrenocorticotropin receptor, which is not engaged by alpha-MSH analogues of this class
Pregnant woman
Harrison's Principles of Internal Medicine (20th ed.)
It does not stick around long enough to make a practical medicine
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