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An in-depth investigation including metagenomics in a single MS patient following FMT not only showed altered composition of gut microbiome with a highly sustained production of SCFAs, improved gait, and no relapse during a year of follow up, but also showed a sustained increase in serum levels of BDNF known to be low in MS (Engen et al., 2020)

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(2020) 127:A5011

We require improved evidence on pharmacokinetics, safety thresholds, and the effects of prolonged exposure

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