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For insulin co-staining, islets were further incubated with anti-insulin antibody (IR002, Dako Agilent Technologies, undiluted) overnight followed by secondary anti-guinea pig Alexa Fluor 647 (A21450, Life Technologies, 1:200) for 1 hour

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This question doesnt have a simple yes-or-no answer

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This could trigger a greater inflammatory response and interfere with the absorption of the medication, leading to unwanted side effects