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Elderly patients may be more sensitive to the medications effects and may require slower titration or lower maintenance doses, particularly if they have reduced renal function or are at higher risk for dehydration from gastrointestinal adverse effects

Remove the plastic cap from the lyophilized tirzepatide vial and the BAC water vial

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The GLP-1 receptor agonist component is considered the likely contributor to gastrointestinal side effects, based on established class-effect data from semaglutide and tirzepatide

The combination of ferroptosis inducers with conventional therapy has shown favorable tolerability and minimal toxicity in preclinical models [188]