One study in healthy adults with normal coagulation (blood clotting) status found that daily supplementation with 1,000 IU (670 mg) of RRR --tocopherol for 12 weeks decreased -carboxylation of prothrombin, a vitamin K-dependent factor in the coagulation cascade (127)
Zhang X, Chen G, Fu X, Wang Y, Zhao Y
Higher weight and weight gain can involve hormones, metabolism, medications, sleep, stress, nutrition, and chronic disease risk
Strategies on how to manage these and other side effects are described in more detail here: Figure 3 of this article and Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with Glp-1 Receptor Agonists
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