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Genotypes 1, 2 and 3 are distributed worldwide, genotype 1 being the predominant one, specifically subtypes 1a and 1b 5
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However, more significant and noticeable weight loss typically occurs after about 8 to 12 weeks of consistent use
Accordingly, VSMC dysfunction ultimately aggravates vascular injury and accelerates the development of atherosclerosis
Patients with diabetes and renal failure represent a special risk group as they have higher morbidity and mortality and are at a higher risk of hypoglycaemia than diabetic individuals with normal renal function
These are elements such as the amount of fat to be treated and individual response to the treatment
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