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In response to different extracellular stimuli, the complex may dissociate and JNK can phosphorylate c-Jun, a component of the activator protein-1 transcription factor
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Another study focusing on melasma (a condition causing blotchy pigmentation on the face) found that using 2% glutathione cream in combination with microneedling led to better fading of melasma patches than microneedling alone
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