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LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma
Unlike peptide-based research compounds, 5-Amino-1MQ is a synthetic small molecule investigated for its potential effects on metabolic processes and cellular energy utilization
One study, aiming to evaluate the potential of glutathione to prevent neurotoxicity associated with cisplatin, studied a 1.5g/m 2 glutathione in 100mL normal saline over 15 minutes, followed by 600mg intramuscular doses on days two to five after cisplatin administration
While preclinical research on NAD+ is compelling, human clinical trial data is still emerging
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