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FIGURE 2 Regarding improved mitochondrial activity, AML cells persistent to treatment with Ara-C in an NSG mouse model presented a higher rate and a genetic signature associated with OxPhos, accompanied by an increase in mitochondrial mass, membrane potential, and ROS production ( in vitro and in vivo ( On the other hand, regarding stable or impaired mitochondrial activity, in Jurkat rho zero (0) T lymphoid cells (cells without mitochondria), there is greater resistance to treatment with bleomycin, an antineoplastic antibiotic, compared to Jurkat cells with mitochondria ( 3.2 Intrinsic and extrinsic mechanistic factors of mitochondrial function mediating chemoresistance in ALs cells There are also intrinsic and extrinsic factors that affect mitochondrial function and, therefore, mediate therapeutic sensitivity

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Bacteriostatic water contains 0.9% benzyl alcohol, which inhibits bacterial growth and keeps your solution safer for multi-use vials

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First, it is appropriate to briefly summarize the pros and cons of the antioxidant assays that were developed previously

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