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Autophagy deficiency in neurons results in buildup of ubiquitinated proteins, dystrophy of neural terminals, impairments in synaptic transmission, and eventually, neurodegeneration observed in both neurodegenerative and neurodevelopmental disorders [245, 249, 250]
Structural flexibility of the Gs -helical domain in the 2-adrenoceptor Gs complex
Melo van Lent D, O'Donnell A, Beiser AS, et al
X-rays and an ultrasound might also follow in diagnostic procedures to note evidence of dilated cardiomyopathy
However, owing to concerns about its teratogenic and potentially mutagenic effects, its use in TB treatment remains experimental and requires further investigation
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