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Another concept is to measure B12 bound to the plasma protein transcobalamin (holoTC, active B12) before and after administration of three high physiological doses of B12 for two days

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J Neurosci 34(21):70677076 Mravec B, Ondicova K, Tillinger A, Pecenak J (2015) Subdiaphragmatic vagotomy enhances stress-induced epinephrine release in rats

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