Mechanisms of Action-Mediated DDIs Furthermore, assessing DDIs for GLP-1 RAs and a dual GLP-1/GIP RA requires additional considerations, including the possible occurrence of DDIs mediated by mechanisms of action that remain poorly understood (Figure 3)
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This suggests that young, female, lower-weight patients may be more susceptible to IGE from GLP-1RA therapy
SGLT2, sodium-glucose cotransporter 2