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The role of short-chain fatty acids in health and disease

Unlike GLP-1 medications, which primarily target metabolic and appetite pathways, 5-amino-1MQ operates through distinct receptors and signaling cascades

The authors reported that in obese mice, daily AOD-9604 administration over 14 days produced significant reductions in body weight gain, decreases in adipose tissue mass, and increases in fat oxidation, with effect sizes comparable to those of full-length human growth hormone [1]

The study further revealed that the combination of AOD9604 and hyaluronic acid injections surpassed the effectiveness of either hyaluronic acid or AOD9604 alone [9]

doi: 10.3390/antiox10050651 6

Schedule: Daily subcutaneous injections for 48 weeks