GLP-1 action may potentially sensitize GIP signaling, which is often compromised in individuals with uncontrolled T2DM
Notice Personal Trigger Foods Keep track of meals that repeatedly seem to worsen indigestion, nausea or diarrhea
Wegovy is FDA-approved for weight loss, so some insurance plans, including BCBS, may be more likely to cover Wegovy for weight loss vs
Regmi and colleagues published a STAR Protocols methods paper detailing differentiation of human subcutaneous adipocytes and measurement of lipolytic function induced by GIP or LY3437943, providing a reproducible in-vitro assay for triagonist research (Regmi et al., 2023, STAR Protocols)
Schedule consultation with a registered dietitian specializing in weight management Establish a structured meal plan that matches the caloric intake you maintained during weight loss (not the deficit that caused loss) Begin daily food logging to build awareness of portion sizes without medication Establish a consistent exercise routine (150+ minutes per week of moderate activity) Identify behavioral strategies that worked during treatment (meal timing, protein targets, specific foods that increased satiety) Set realistic expectations: some regain is likely
For every molecule of insulin secreted, an equal amount of C-peptide enters the bloodstream