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Continue regular escalation every 4 weeks until reaching the target maintenance dosage of 2.4 mg once weekly

(1996): Effects of anticholinesterase drugs tacrine and E2020, the 5-HT3 antagonist ondansentron, and the H3 antagonist thioperamide, in models of cognition and cholinergic function

For compounded formulations, these are state-licensed compounding pharmacies that prepare medications based on individual prescriptions

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Reported or proposed issue Liver or metabolic changes Evidence source Animal studies and pathway theory Known or theoretical