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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

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Whole blood stimulation was terminated by adding 1.3 ml of RNA later Stabilization Solution (Thermo Fisher Scientific, Altrincham, UK)

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Heres the testing dose structure: 1 mg or 2 mg as the starting dose 4 mg 8 mg 12 mg The highest dose tested was 12 mg per week