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As a novel antidiabetic agent, glucagon-like peptide-1 (GLP-1) exerts a renoprotective effect in DKD rats via activation of autophagy through AMPK-mTOR pathway (155)

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It is possible that the amount of muscle damage and inflammation was so great during this study that administration of antioxidants had no possible benefit or as noted could possibly have had enhanced the response[27]

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