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But individual response varies
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In these studies, patients experienced elevated rates of adverse reactions, including weight loss, decreased BMI, decreased appetite, insomnia, infections (upper respiratory and nasopharyngitis), irritability, and affect lability
The American Journal of Clinical Nutrition , 69 (6), 11351143
For HOMA-IR, doseresponse modeling suggested favorable reductions with all three evaluated supplements, with mean effective doses estimated at 1,741 mg/day for L-carnitine, 5,137 mg/day for inulin, and 4,988 mg/day for LC n3-PUFA
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