While safe at therapeutic doses of up to 4 g per day for adults, APAP overdoses, either accidental or intentional, are one of the leading causes of acute liver failure in the United States [33]
Due to the higher risks associated with injections, it should only be done under medical supervision
Daratumumab targets a different epitope on CD38 and induces cell death through ADCC, complement-dependent cytotoxicity (CDC), and direct damage to myeloma cells
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Nature 434 (7033), 658662
Questo doppio ruolo promuove un rimodellamento ordinato della matrice