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The experimental procedures were performed complying with the Guide for the Care and Use of Laboratory Animals of China Medical University and approved by the Animal Care and Use Committee of China Medical University (Issue No

In human studies, translation remains limited, as clinical trials are generally small, short-term and heterogeneous in design, dosing and endpoints, with some reporting no significant effects

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Some patients benefit from fiber supplements or stool softeners under medical guidance

For older adults with cardiovascular risk factors, this benefit can tip the risk-benefit calculation meaningfully in favor of treatment

The obtained spectra were background-corrected